Many authors in the treatment of purulent meningitis is recommended to combine massive doses of penicillin in with one of the antibiotics (chloramphenicol, streptomycin) or sulfonamides. When pfeyfferovskom, Salmonella and fridlenderovskom meningitis has the best effect chloramphenicol, usually assigned in combination with streptomycin. In some cases of meningitis caused by Haemophilus influenzae Afanasiev – Pfeiffer, effective tetracyclines. Chloramphenicol administered in a single dose of 0,015 g per 1 kg of the patient's weight (when introduced into the candlelight appoint two dose). The drug is given at intervals of 4-6 h.

Intramuscular antibiotics, as well as use them in, should be continued until complete disappearance of the meningeal symptoms, persistent normalization of temperature and blood, and also reduce cytosis in the cerebrospinal fluid to normal numbers. To combat the toxemia is first necessary to ensure the introduction of sufficient quantities of fluid (drinking plenty of fluids, intravenous and subcutaneous of glucose, saline, plasma or blood transfusion, etc.). Introduction of fluid required and in the cases that occur with swelling and edema of the brain, since the development of the latter is primarily a consequence of toxicosis. Simultaneously, the dehydration: intramuscular magnesium sulfate, intravenous hypertonic solutions of glucose, sodium chloride or calcium, the use of diuretics (gipotiazid, novurita, etc.), intranasal constant giving 40 – 50% mixture of oxygen. In threatening swelling of the brain growth of the symptoms – respiratory arrhythmia, bradycardia, convulsions, high blood pressure should be immediate introduction merkuzala, 100-150 mg of cortisone. Plays an important role and symptomatic therapy.

Assign chlorpromazine, amidopirin, drugs and sleeping pills, heart means, chloral hydrate in enemas. There is no doubt the importance of good care, proper hygiene regime, nutrition, rich in vitamins (vitamin B1 in this case is assigned as an injection). With the development of the syndrome Waterhouse – Friedrichs treatment should begin with intravenous (worse subcutaneous) administration of a mixture of saline with 5% glucose solution at a rate of 40-60 drops per minute.

Saturday, March 13th, 2021 News